Biological hazard applications: overview and procedure

EFSA has implemented a number of provisional measures – such as all staff being required to work from home – in order to comply with the restrictions in place to control the spread of COVID-19. To ensure business continuity on regulated product applications in these circumstances, EFSA will allow companies and institutions to share documentation with the Authority through their chosen internet-based software. For more information, including contact details, consult the Services for applicants page.


In the field of biological hazards, EFSA evaluates applications in two scientific areas: animal by-product treatments and decontamination substances other than potable water for food of animal origin.

Animal by-product treatment

Some animal by-products not intended for human consumption may be used for the production of technical or industrial products. EFSA evaluates the safety of these alternative animal by-product treatments.

Applications should be submitted to the national competent authority of a Member State. EFSA carries out the risk assessment whilst the European Commission decides whether or not to authorise the alternative method.

Decontamination substances

All substances other than potable water used for the removal of microbial surface contamination of foods of animal origin require prior authorisation. Applications should be submitted to the European Commission. EFSA evaluates the safety and efficacy of these ‘decontamination substances’.

Decontamination substances application procedure